-0.7 C
Washington

Baricitinib, a drug that promises to fight alopecia areata: this is how it works

Date:

Share:

Commonly used to treat autoimmune diseases such as rheumatoid arthritis, the drug has been approved by the US Food and Drug Administration for systemic treatment.

Baricitinib Is the name of the approved drug US Food and Drug Administration (FDA, an acronym in English) Alopecia areata ,therefore, First systemic treatment Treat her.

Alopecia areata is a disease that affects both genders and Prone to children and young adults Explain the medical manual MSD..

The first signs of this disease are Gradually remove hair from head and beard That is, only part of this skin loses hair and remains Absence of rounded or irregular shapes ..

According to various experts, the cause is Autoimmune status That is, the immune system that protects the body damages itself.

For alopecia areata The body’s defenses mistakenly attack the hair follicles, which do not develop properly, resulting in hair loss. The manual says.

Baricitinib for alopecia areata

Drugs approved by FDA Consists of Orally ingested tablets “For treatment of Adult patient with severe alopecia areata “, The administrator wrote a statement.

What does this medicine do Inhibits Janus kinase Also known as the protein family Jack .. They block the activity of one or more specific enzyme families and play a role in blocking the pathways that cause inflammation.

according to Dermatologist at Clinica Santa Maria, Marcelo Refimil ,medicine It is used in the country “to treat rheumatoid arthritis, another autoimmune disease” ..

To obtain FDA approval, the company behind the drug, Olumiant, conducted two “randomized, double-blind, placebo-controlled” trials.

In both studies, Subjects received a placebo dose, 2 milligrams of drug, or 4 milligrams daily ..

Alopecia areata-Alopecia areata-Severe
Patients with severe alopecia areata | MSD Medical Manual

The results showed that All patients in both studies had an increase in hair growth of 17% or more from the minimum measured value of the drug. Compared to Those who received placebo, those who showed an increase of 5% or less ..

Side effects of the drug

However, despite the good results obtained with this drug in the treatment of severe alopecia areata The same company web page The negative effects can range from headaches to more serious complications such as an increased risk of cancer and death in people over the age of 50 suffering from heart-related illnesses. ..

The The most common side effects Is it Infection Upper and lower respiratory tract or urinary tract, headache Appearance Acne , High cholesterol (Hyperlipidemia), an increase in the enzyme called Creatine phosphokinase With Liver enzyme , Hair follicle inflammation (Folliculitis), nausea , Genital yeast infection (Candida infection), anemia Low numbers of certain types of white blood cells (Neutropenia ), stomach ache , Herpes With shingles Weight gain Warn the FDA.

On the other hand, laboratory list Serious infection ,gain Risk of cardiovascular problems such as heart attack Likely to suffer cancer Develop Blood clot Conditions related to Gastrointestinal tract , Allergic reaction Y Changes in blood test results what Less common side effects ..

Source: Biobiochile

Subscribe to our magazine

full,length,photo,of,pretty,young,woman,showing,peace,gesture

━ more like this

Five American police officers accused of murdering a 29-year-old man in Tennessee

Investigation of police colleagues who tried to help cover up the factsProsecutors in Memphis, Tennessee, have filed charges against five police officers for the...

Five US police officers charged with murder of 29-year-old man in Tennessee

Investigation of police colleagues who tried to help cover up the factsProsecutors in Memphis, Tennessee, have filed charges against five police officers for the...

LEAVE A REPLY

Please enter your comment!
Please enter your name here