“Nsp1” is the name of the new protein the researchers identified. The discovery could enable experts to create new treatments to fight the virus. To date, treatments focus only on attacking the pathogen’s “spike” protein.
Since the development of vaccines and treatments to combat the disease, coronavirus most of them focused on attack proteins “spike” It lies on the surface and gives the virus a characteristic coronal appearance.
Through a statement, researchers at the University of Geneva said, “This small protein selectively blocks the ribosomes, the cell’s ‘factories’, rendering them unavailable and impeding the immune response, while simultaneously stimulating the production of viral proteins. explained. .
of Nsp1 is one of 16 known nonstructural proteins of the SARS-CoV-2 virus that causes COVID-19. it is essential to reproduce.
Learn more about research on novel coronavirus proteins
To study it, the university performed simulations with algorithms, followed by experimental evaluation methods and X-ray crystallography to identify it as a possible target for future pharmaceuticals. confirmed.
Experts have found one in particular, testing whether several molecules can bind to target proteins and serve as potential vehicles for new therapeutics. 5-Acetylaminoindane has a lot of potential, the statement said.
The study highlights that these advances could be useful not only against novel coronavirus variants that threaten to prolong pandemics, but also against other similar viruses.