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Nobel Prize in Chemistry Awarded to Expert Who Developed Tools to Build Molecules

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The prize was awarded to three scientists from Denmark and the United States. American Barry Sharpless becomes her fifth person to win her second Nobel Prize.

scientists Carolyn Bertozzi, Morten Meldall, K. Barry Sharpless This year’s Nobel Prize winner in chemistry.

Researchers “out-of-the-box” tools for building molecules, The Swedish Academy of Sciences in Stockholm announced on Wednesday (10 May 2022).

The Academy emphasized that this year’s Nobel Prize is for “development of click chemistry and bioorthogonal chemistry.” Contributing to the improvement of anticancer drugs.

This year’s winners’ research “expands[chemical]frontiers and has a major impact on science and society.”

“Click chemistry is used in drug development to map DNA and create materials that are better suited for their purpose,” they explained.

Using bioorthogonal reactions, researchers have improved the targeting of cancer drugs.

click chemistry

Award Rewards Works Add and Treat Academy “Making a difficult process easy” .

“Click chemistry and bioorthogonal reactions have ushered chemistry into the age of functionalism,” they said.

The Swedish Academy recalled that “chemists have long been driven by the desire to build more complex molecules”.

“Pharmaceutical research often recreates naturally occurring molecules with medicinal properties,” they say.

This has yielded many impressive molecular constructs, but they are generally slow to make and very expensive.

Second Nobel Prize in Chemistry

K. Barry Sharpless, a two-time Nobel laureate in chemistry, began “to get the ball rolling,” according to the Academy, and he coined the concept of “click chemistry,” a form of chemistry in which reactions take place. I remembered that Fast and unwanted side effects are avoided.

Shortly thereafter, Meldal and Sharpless independently published copper-catalyzed azide-alkyne cycloadditions, which are currently the pinnacle of click chemistry.

“This is an elegant and efficient chemical reaction that is widely used today. It is used in drug development, mapping DNA and making materials better suited for their purpose, among many other applications.

This is the last of the 2022 Nobel Prizes in Science, after the announcement of the prize in medicine on Monday and the prize in physics yesterday Tuesday.



Source: Biobiochile

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